Linkage Lab is an interactive Shiny app for exploring how genetic linkage between markers affects likelihood ratios (LR) in kinship testing.
For a given pedigree comparison the app shows how the LR for a pair of markers is influenced by:
- the observed genotypes
- recombination rate between the markers
- the allele frequencies
- the mutation rate
The app is built on the pedsuite.
- Duo – Unrelated
- Sibs – Unrelated
- Half sibs – Unrelated
- Grandparent – Unrelated
- Avuncular – Unrelated
- Duo – Sibs
- Sibs – Half sibs
- Grandparent – Half sibs
- Avuncular – Half sibs
- Grandparent – Avuncular